When a single father to a teenage daughter learns that he has a fatal brain tumor, he takes her on a road trip to find the mother who abandoned her years before and to try to teach her everything she might need over the rest of her life.
A dying mother, Sarah, tells her last wish to her eldest son, Drew, that he take his younger brother, Will, to the place they were born. Despite tragic family history, hope gives promise to the future.
某日，布莱恩（约翰尼·梅辛纳 Johnny Messner 饰）孤身一人在广袤无垠的沙漠之中醒来，失去了记忆的他不知道自己身处何地，为何在此，甚至不知道自己究竟是谁，有着怎样的身份和过去。他唯一的陪伴是身边躺着的八具尸体，以及塞满了可卡因和钞票的两辆面包车。 很快，大毒枭马特奥（丹尼·特乔 Danny Trejo 饰）以及他的爪牙便找上了布莱恩…
